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SORAFENIB TOSYLATE

Sorafenib tosylate

CAS: 475207-59-1;4750207-59-1

Molecular Formula: C28H24ClF3N4O6S

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SORAFENIB TOSYLATE - Names and Identifiers

Name Sorafenib tosylate
Synonyms BAY43-9006
BAY 43-9006
SORAFENIB-D3
SORAFENIB TOSYLATE
Sorafenib tosylate
Sorafinib mesylate
Sorafenib Tosylate(Bay 43-9006,Nexavar)
SORAFENIB TOSYLATE (BAY 43-9006 TOSYLATE)
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea Tolsylate
4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N2-methylpyridine-2-carboxamide mono (4-methylbenzenesulfonate)
4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide monomethanesulfonate
CAS 475207-59-1
4750207-59-1
EINECS 641-758-8

SORAFENIB TOSYLATE - Physico-chemical Properties

Molecular FormulaC28H24ClF3N4O6S
Molar Mass637.03
Melting Point229-232°C
Solubility Soluble in water (<1 mg/ml) at 25 °C, DMSO (127 mg/ml) at 25 °C, and ethanol (<1
Appearancesolid
ColorOff-white
Storage Condition2-8°C(protect from light)
StabilityStable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
UseAn inhibitor of Flk-1 (VEGFR), PDGFR and Raf kinases.

SORAFENIB TOSYLATE - Risk and Safety

Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS28 - After contact with skin, wash immediately with plenty of soap-suds.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
HS Code29159000

SORAFENIB TOSYLATE - Introduction

Sorafenib Tosylate are tyrosine kinases (VEGFR and PDGFR) and RAF/MEK/ERK cascade inhibitors, acting simultaneously on Raf-1,wtBRAF and V599EBRAF, with IC50 of 6 nM, 22 nM and 38 nM, respectively.
Last Update：2022-10-16 17:25:22
SORAFENIB TOSYLATE
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Jiangsu Pules Biotechnology Co.,Ltd.
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CAS: 475207-59-1
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MedChemExpress (MCE)
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Shanghai Worldyang Chemical Co.,Ltd.
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Mobile: +86-13651600618
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Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: Sorafenib tosylate Request for quotation
CAS: 475207-59-1
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CHEMBSF (Shanghai) Biomedical Technology Co., Ltd
Spot supply
Product Name: Sorafenib tosylate Request for quotation
CAS: 475207-59-1
Tel: +86-18721521379
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: Sorafenib tosylate Request for quotation
CAS: 475207-59-1
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Wechat: chemical6666 
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: Bay 43-9006 Tosylate Visit Supplier Webpage Request for quotation
CAS: 475207-59-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
　　　　 tech@medchemexpress.com
Mobile: 609-228-6898
BOC Sciences
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Product Name: Sorafenib tosylate Visit Supplier Webpage Request for quotation
CAS: 475207-59-1
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
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Product List: View Catalog
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Sorafenib tosylate Visit Supplier Webpage Request for quotation
CAS: 475207-59-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Sorafenib tosylate Visit Supplier Webpage Request for quotation
CAS: 475207-59-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Sorafenib Tosylate Visit Supplier Webpage Request for quotation
CAS: 475207-59-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Shanghai Worldyang Chemical Co.,Ltd.
Product Name: Sorafenib tosylate Request for quotation
CAS: 475207-59-1
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228 Click to send a QQ message
Wechat: +8613651600618
WhatsApp: +8613651600618
View History
SORAFENIB TOSYLATE
3,4-二羟基-Β-苯乙胺
1-(苯基磺酰基)-2,5-二氢-1H-吡咯
1-氯吡咯并[1,2-C]嘧啶
3-乙氧基-5-(甲氧羰基)苯基硼酸,频哪醇酯
4-氯-2-甲氧基苯基硼酸
4-溴-6-甲基-1H-吡唑并[3,4-C]吡啶-7-酮
(S)-2-(((叔丁基二甲基甲硅烷基)氧基)二苯基甲基)吡咯烷
鲸蜡硬脂醇和鲸蜡硬脂醇聚醚-20
AMMONIUM CHLORIDE-HYDROXIDE BUFFER
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